Clinical proteomics: A need to define the field and to begin to set adequate standards
Identifieur interne : 009193 ( Main/Exploration ); précédent : 009192; suivant : 009194Clinical proteomics: A need to define the field and to begin to set adequate standards
Auteurs : Harald Mischak [Allemagne] ; Rolf Apweiler [Royaume-Uni] ; Rosamonde E. Banks [Royaume-Uni] ; Mark Conaway [États-Unis] ; Joshua Coon [États-Unis] ; Anna Dominiczak [Royaume-Uni] ; Jochen H. H. Ehrich [Allemagne] ; Danilo Fliser [Allemagne] ; Mark Girolami [Royaume-Uni] ; Henning Hermjakob [Royaume-Uni] ; Denis Hochstrasser [Allemagne, Suisse] ; Joachim Jankowski [Allemagne] ; Bruce A. Julian [États-Unis] ; Walter Kolch [Royaume-Uni] ; Ziad A. Massy [France] ; Christian Neusuess [Allemagne] ; Jan Novak [États-Unis] ; Karlheinz Peter [Australie] ; Kasper Rossing [Danemark] ; Joost Schanstra [France] ; O. John Semmes [États-Unis] ; Dan Theodorescu [États-Unis] ; Visith Thongboonkerd [Thaïlande] ; Eva M. Weissinger [Allemagne] ; Jennifer E. Van Eyk [États-Unis] ; Tadashi Yamamoto [Japon]Source :
- PROTEOMICS – Clinical Applications [ 1862-8346 ] ; 2007-02.
Descripteurs français
- Wicri :
- topic : Traitement des données, Protocole.
English descriptors
- KwdEn :
- Abundant proteins, Analytical approach, Analytical performance, Analytical platforms, Appl, Application platform, Appropriate quality control, Assay, Biomarker, Biomarker discovery, Biomarkers, Body fluids, Cancer inst, Cancer research, Clear definition, Clin, Clinical, Clinical centre, Clinical conditions, Clinical data, Clinical diagnosis, Clinical platform, Clinical practice, Clinical problem, Clinical proteomic studies, Clinical proteomic study, Clinical proteomics, Clinical proteomics studies, Clinical proteomics study, Clinical study, Clinical trials, Clinician, Data analysis, Data processing, Datasets, Development pipeline, Diagnostics, Different groups, Different samples, Discovery platform, Dynamic ranges, Entire process, Epidemiological studies, Gmbh, Guideline, Hannover, Kgaa, Laboratory practice, Large number, Many studies, Mischak, Molecular signature, Past experience, Pilot study, Potential biomarkers, Precise definition, Proteome, Proteome analysis, Proteome data, Proteomic, Proteomic analyses, Proteomics, Proteomics clin, Protocol, Quality control, Quality control criteria, Relative quantification, Reproducibility, Same sample, Sample preparation, Sample processing, Scientific community, Specific disease, Study design, Such demand, Sufficient details, Utmost importance, Validation, Various stages, Verlag, Verlag gmbh, Weinheim, Weinheim proteomics clin.
- Teeft :
- Abundant proteins, Analytical approach, Analytical performance, Analytical platforms, Appl, Application platform, Appropriate quality control, Assay, Biomarker, Biomarker discovery, Biomarkers, Body fluids, Cancer inst, Cancer research, Clear definition, Clin, Clinical, Clinical centre, Clinical conditions, Clinical data, Clinical diagnosis, Clinical platform, Clinical practice, Clinical problem, Clinical proteomic studies, Clinical proteomic study, Clinical proteomics, Clinical proteomics studies, Clinical proteomics study, Clinical study, Clinical trials, Clinician, Data analysis, Data processing, Datasets, Development pipeline, Diagnostics, Different groups, Different samples, Discovery platform, Dynamic ranges, Entire process, Epidemiological studies, Gmbh, Guideline, Hannover, Kgaa, Laboratory practice, Large number, Many studies, Mischak, Molecular signature, Past experience, Pilot study, Potential biomarkers, Precise definition, Proteome, Proteome analysis, Proteome data, Proteomic, Proteomic analyses, Proteomics, Proteomics clin, Protocol, Quality control, Quality control criteria, Relative quantification, Reproducibility, Same sample, Sample preparation, Sample processing, Scientific community, Specific disease, Study design, Such demand, Sufficient details, Utmost importance, Validation, Various stages, Verlag, Verlag gmbh, Weinheim, Weinheim proteomics clin.
Abstract
The aim of this manuscript is to initiate a constructive discussion about the definition of clinical proteomics, study requirements, pitfalls and (potential) use. Furthermore, we hope to stimulate proposals for the optimal use of future opportunities and seek unification of the approaches in clinical proteomic studies. We have outlined our collective views about the basic principles that should be considered in clinical proteomic studies, including sample selection, choice of technology and appropriate quality control, and the need for collaborative interdisciplinary efforts involving clinicians and scientists. Furthermore, we propose guidelines for the critical aspects that should be included in published reports. Our hope is that, as a result of stimulating discussion, a consensus will be reached amongst the scientific community leading to guidelines for the studies, similar to those already published for mass spectrometric sequencing data. We contend that clinical proteomics is not just a collection of studies dealing with analysis of clinical samples. Rather, the essence of clinical proteomics should be to address clinically relevant questions and to improve the state‐of‐the‐art, both in diagnosis and in therapy of diseases.
Url:
DOI: 10.1002/prca.200600771
Affiliations:
- Allemagne, Australie, Danemark, France, Japon, Royaume-Uni, Suisse, Thaïlande, États-Unis
- Alabama, Basse-Saxe, Berlin, Canton de Genève, Hauts-de-France, Maryland, Midi-Pyrénées, Occitanie (région administrative), Picardie, Victoria (État), Virginie, Wisconsin, Écosse
- Amiens, Berlin, Genève, Glasgow, Hanovre, Melbourne, Toulouse
- Université de Genève, Université de Glasgow
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Le document en format XML
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Ehrich</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Hannover Medical School, Department of Pediatrics, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Fliser, Danilo" sort="Fliser, Danilo" uniqKey="Fliser D" first="Danilo" last="Fliser">Danilo Fliser</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Hannover Medical School, Department of Nephrology, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Girolami, Mark" sort="Girolami, Mark" uniqKey="Girolami M" first="Mark" last="Girolami">Mark Girolami</name><affiliation wicri:level="4"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Computing Science, University of Glasgow, Glasgow</wicri:regionArea><orgName type="university">Université de Glasgow</orgName><placeName><settlement type="city">Glasgow</settlement><region type="country">Écosse</region></placeName></affiliation></author><author><name sortKey="Hermjakob, Henning" sort="Hermjakob, Henning" uniqKey="Hermjakob H" first="Henning" last="Hermjakob">Henning Hermjakob</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton</wicri:regionArea><wicri:noRegion>Hinxton</wicri:noRegion></affiliation></author><author><name sortKey="Hochstrasser, Denis" sort="Hochstrasser, Denis" uniqKey="Hochstrasser D" first="Denis" last="Hochstrasser">Denis Hochstrasser</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Charité (CBF), Medizinische Klinik IV, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation><affiliation wicri:level="4"><country xml:lang="fr">Suisse</country><wicri:regionArea>Biomedical Proteomics Research Group, Department of Structural Biology and Bioinformatics, Faculty of Medicine, University of Geneva, Geneva</wicri:regionArea><orgName type="university">Université de Genève</orgName><placeName><settlement type="city">Genève</settlement><region nuts="3" type="region">Canton de Genève</region></placeName></affiliation></author><author><name sortKey="Jankowski, Joachim" sort="Jankowski, Joachim" uniqKey="Jankowski J" first="Joachim" last="Jankowski">Joachim Jankowski</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Charite‐Universitatsmedizin Berlin, Berlin</wicri:regionArea><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Julian, Bruce A" sort="Julian, Bruce A" uniqKey="Julian B" first="Bruce A." last="Julian">Bruce A. Julian</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, University of Alabama at Birmingham, Birmingham, AL</wicri:regionArea><placeName><region type="state">Alabama</region></placeName></affiliation></author><author><name sortKey="Kolch, Walter" sort="Kolch, Walter" uniqKey="Kolch W" first="Walter" last="Kolch">Walter Kolch</name><affiliation wicri:level="1"><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Beatson Institute for Cancer Research, Glasgow</wicri:regionArea><wicri:noRegion>Glasgow</wicri:noRegion></affiliation></author><author><name sortKey="Massy, Ziad A" sort="Massy, Ziad A" uniqKey="Massy Z" first="Ziad A." last="Massy">Ziad A. Massy</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>INSERM ERI‐12, Amiens, France and Amiens University Hospital, UPJV, Amiens</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Picardie</region><settlement type="city">Amiens</settlement></placeName></affiliation></author><author><name sortKey="Neusuess, Christian" sort="Neusuess, Christian" uniqKey="Neusuess C" first="Christian" last="Neusuess">Christian Neusuess</name><affiliation wicri:level="1"><country xml:lang="fr">Allemagne</country><wicri:regionArea>University of Aalen, Aalen</wicri:regionArea><wicri:noRegion>Aalen</wicri:noRegion><wicri:noRegion>Aalen</wicri:noRegion></affiliation></author><author><name sortKey="Novak, Jan" sort="Novak, Jan" uniqKey="Novak J" first="Jan" last="Novak">Jan Novak</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL</wicri:regionArea><placeName><region type="state">Alabama</region></placeName></affiliation></author><author><name sortKey="Peter, Karlheinz" sort="Peter, Karlheinz" uniqKey="Peter K" first="Karlheinz" last="Peter">Karlheinz Peter</name><affiliation wicri:level="3"><country xml:lang="fr">Australie</country><wicri:regionArea>Baker Heart Research Institute, Melbourne</wicri:regionArea><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Rossing, Kasper" sort="Rossing, Kasper" uniqKey="Rossing K" first="Kasper" last="Rossing">Kasper Rossing</name><affiliation wicri:level="1"><country xml:lang="fr">Danemark</country><wicri:regionArea>Steno Diabetes Center, Gentofte</wicri:regionArea><wicri:noRegion>Gentofte</wicri:noRegion></affiliation></author><author><name sortKey="Schanstra, Joost" sort="Schanstra, Joost" uniqKey="Schanstra J" first="Joost" last="Schanstra">Joost Schanstra</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Inserm, U388, Toulouse</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Midi-Pyrénées</region><settlement type="city">Toulouse</settlement></placeName></affiliation></author><author><name sortKey="Semmes, O John" sort="Semmes, O John" uniqKey="Semmes O" first="O. John" last="Semmes">O. John Semmes</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, VA</wicri:regionArea><placeName><region type="state">Virginie</region></placeName></affiliation></author><author><name sortKey="Theodorescu, Dan" sort="Theodorescu, Dan" uniqKey="Theodorescu D" first="Dan" last="Theodorescu">Dan Theodorescu</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Urology and Mellon Prostate Cancer Institute, University of Virginia, Charlottesville, VA</wicri:regionArea><placeName><region type="state">Virginie</region></placeName></affiliation></author><author><name sortKey="Thongboonkerd, Visith" sort="Thongboonkerd, Visith" uniqKey="Thongboonkerd V" first="Visith" last="Thongboonkerd">Visith Thongboonkerd</name><affiliation wicri:level="1"><country xml:lang="fr">Thaïlande</country><wicri:regionArea>Faculty of Medicine at Siriraj Hospital, Mahidol University, Bangkok</wicri:regionArea><wicri:noRegion>Bangkok</wicri:noRegion></affiliation></author><author><name sortKey="Weissinger, Eva M" sort="Weissinger, Eva M" uniqKey="Weissinger E" first="Eva M." last="Weissinger">Eva M. Weissinger</name><affiliation wicri:level="3"><country xml:lang="fr">Allemagne</country><wicri:regionArea>Hannover Medical School, Department of Hematology, Hemostasis and Oncology, Hannover</wicri:regionArea><placeName><region type="land" nuts="2">Basse-Saxe</region><settlement type="city">Hanovre</settlement></placeName></affiliation></author><author><name sortKey="Van Eyk, Jennifer E" sort="Van Eyk, Jennifer E" uniqKey="Van Eyk J" first="Jennifer E." last="Van Eyk">Jennifer E. Van Eyk</name><affiliation wicri:level="2"><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Medicine, Johns Hopkins University, Baltimore, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Yamamoto, Tadashi" sort="Yamamoto, Tadashi" uniqKey="Yamamoto T" first="Tadashi" last="Yamamoto">Tadashi Yamamoto</name><affiliation wicri:level="1"><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Structural Pathology, Institute of Nephrology, Niigata University Graduate School of Medical and Dental Sciences, Niigata</wicri:regionArea><wicri:noRegion>Niigata</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">PROTEOMICS – Clinical Applications</title><title level="j" type="alt">PROTEOMICS CLINICAL APPLICATIONS</title><idno type="ISSN">1862-8346</idno><idno type="eISSN">1862-8354</idno><imprint><biblScope 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definition</term><term>Clin</term><term>Clinical</term><term>Clinical centre</term><term>Clinical conditions</term><term>Clinical data</term><term>Clinical diagnosis</term><term>Clinical platform</term><term>Clinical practice</term><term>Clinical problem</term><term>Clinical proteomic studies</term><term>Clinical proteomic study</term><term>Clinical proteomics</term><term>Clinical proteomics studies</term><term>Clinical proteomics study</term><term>Clinical study</term><term>Clinical trials</term><term>Clinician</term><term>Data analysis</term><term>Data processing</term><term>Datasets</term><term>Development pipeline</term><term>Diagnostics</term><term>Different groups</term><term>Different samples</term><term>Discovery platform</term><term>Dynamic ranges</term><term>Entire process</term><term>Epidemiological studies</term><term>Gmbh</term><term>Guideline</term><term>Hannover</term><term>Kgaa</term><term>Laboratory practice</term><term>Large number</term><term>Many studies</term><term>Mischak</term><term>Molecular signature</term><term>Past experience</term><term>Pilot study</term><term>Potential biomarkers</term><term>Precise definition</term><term>Proteome</term><term>Proteome analysis</term><term>Proteome data</term><term>Proteomic</term><term>Proteomic analyses</term><term>Proteomics</term><term>Proteomics clin</term><term>Protocol</term><term>Quality control</term><term>Quality control criteria</term><term>Relative quantification</term><term>Reproducibility</term><term>Same sample</term><term>Sample preparation</term><term>Sample processing</term><term>Scientific community</term><term>Specific disease</term><term>Study design</term><term>Such demand</term><term>Sufficient details</term><term>Utmost importance</term><term>Validation</term><term>Various stages</term><term>Verlag</term><term>Verlag gmbh</term><term>Weinheim</term><term>Weinheim proteomics clin</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Abundant proteins</term><term>Analytical approach</term><term>Analytical performance</term><term>Analytical platforms</term><term>Appl</term><term>Application platform</term><term>Appropriate quality control</term><term>Assay</term><term>Biomarker</term><term>Biomarker discovery</term><term>Biomarkers</term><term>Body fluids</term><term>Cancer inst</term><term>Cancer research</term><term>Clear definition</term><term>Clin</term><term>Clinical</term><term>Clinical centre</term><term>Clinical conditions</term><term>Clinical data</term><term>Clinical diagnosis</term><term>Clinical platform</term><term>Clinical practice</term><term>Clinical problem</term><term>Clinical proteomic studies</term><term>Clinical proteomic study</term><term>Clinical proteomics</term><term>Clinical proteomics studies</term><term>Clinical proteomics study</term><term>Clinical study</term><term>Clinical trials</term><term>Clinician</term><term>Data analysis</term><term>Data processing</term><term>Datasets</term><term>Development pipeline</term><term>Diagnostics</term><term>Different groups</term><term>Different samples</term><term>Discovery platform</term><term>Dynamic ranges</term><term>Entire process</term><term>Epidemiological studies</term><term>Gmbh</term><term>Guideline</term><term>Hannover</term><term>Kgaa</term><term>Laboratory practice</term><term>Large number</term><term>Many studies</term><term>Mischak</term><term>Molecular signature</term><term>Past experience</term><term>Pilot study</term><term>Potential biomarkers</term><term>Precise definition</term><term>Proteome</term><term>Proteome analysis</term><term>Proteome data</term><term>Proteomic</term><term>Proteomic analyses</term><term>Proteomics</term><term>Proteomics clin</term><term>Protocol</term><term>Quality control</term><term>Quality control criteria</term><term>Relative quantification</term><term>Reproducibility</term><term>Same sample</term><term>Sample preparation</term><term>Sample processing</term><term>Scientific community</term><term>Specific disease</term><term>Study design</term><term>Such demand</term><term>Sufficient details</term><term>Utmost importance</term><term>Validation</term><term>Various stages</term><term>Verlag</term><term>Verlag gmbh</term><term>Weinheim</term><term>Weinheim proteomics clin</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Traitement des données</term><term>Protocole</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The aim of this manuscript is to initiate a constructive discussion about the definition of clinical proteomics, study requirements, pitfalls and (potential) use. Furthermore, we hope to stimulate proposals for the optimal use of future opportunities and seek unification of the approaches in clinical proteomic studies. We have outlined our collective views about the basic principles that should be considered in clinical proteomic studies, including sample selection, choice of technology and appropriate quality control, and the need for collaborative interdisciplinary efforts involving clinicians and scientists. Furthermore, we propose guidelines for the critical aspects that should be included in published reports. Our hope is that, as a result of stimulating discussion, a consensus will be reached amongst the scientific community leading to guidelines for the studies, similar to those already published for mass spectrometric sequencing data. We contend that clinical proteomics is not just a collection of studies dealing with analysis of clinical samples. Rather, the essence of clinical proteomics should be to address clinically relevant questions and to improve the state‐of‐the‐art, both in diagnosis and in therapy of diseases.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Danemark</li><li>France</li><li>Japon</li><li>Royaume-Uni</li><li>Suisse</li><li>Thaïlande</li><li>États-Unis</li></country><region><li>Alabama</li><li>Basse-Saxe</li><li>Berlin</li><li>Canton de Genève</li><li>Hauts-de-France</li><li>Maryland</li><li>Midi-Pyrénées</li><li>Occitanie (région administrative)</li><li>Picardie</li><li>Victoria (État)</li><li>Virginie</li><li>Wisconsin</li><li>Écosse</li></region><settlement><li>Amiens</li><li>Berlin</li><li>Genève</li><li>Glasgow</li><li>Hanovre</li><li>Melbourne</li><li>Toulouse</li></settlement><orgName><li>Université de Genève</li><li>Université de Glasgow</li></orgName></list><tree><country name="Allemagne"><region name="Basse-Saxe"><name sortKey="Mischak, Harald" sort="Mischak, Harald" uniqKey="Mischak H" first="Harald" last="Mischak">Harald Mischak</name></region><name sortKey="Ehrich, Jochen H H" sort="Ehrich, Jochen H H" uniqKey="Ehrich J" first="Jochen H. H." last="Ehrich">Jochen H. H. Ehrich</name><name sortKey="Fliser, Danilo" sort="Fliser, Danilo" uniqKey="Fliser D" first="Danilo" last="Fliser">Danilo Fliser</name><name sortKey="Hochstrasser, Denis" sort="Hochstrasser, Denis" uniqKey="Hochstrasser D" first="Denis" last="Hochstrasser">Denis Hochstrasser</name><name sortKey="Jankowski, Joachim" sort="Jankowski, Joachim" uniqKey="Jankowski J" first="Joachim" last="Jankowski">Joachim Jankowski</name><name sortKey="Neusuess, Christian" sort="Neusuess, Christian" uniqKey="Neusuess C" first="Christian" last="Neusuess">Christian Neusuess</name><name sortKey="Weissinger, Eva M" sort="Weissinger, Eva M" uniqKey="Weissinger E" first="Eva M." last="Weissinger">Eva M. Weissinger</name></country><country name="Royaume-Uni"><noRegion><name sortKey="Apweiler, Rolf" sort="Apweiler, Rolf" uniqKey="Apweiler R" first="Rolf" last="Apweiler">Rolf Apweiler</name></noRegion><name sortKey="Banks, Rosamonde E" sort="Banks, Rosamonde E" uniqKey="Banks R" first="Rosamonde E." last="Banks">Rosamonde E. Banks</name><name sortKey="Dominiczak, Anna" sort="Dominiczak, Anna" uniqKey="Dominiczak A" first="Anna" last="Dominiczak">Anna Dominiczak</name><name sortKey="Girolami, Mark" sort="Girolami, Mark" uniqKey="Girolami M" first="Mark" last="Girolami">Mark Girolami</name><name sortKey="Hermjakob, Henning" sort="Hermjakob, Henning" uniqKey="Hermjakob H" first="Henning" last="Hermjakob">Henning Hermjakob</name><name sortKey="Kolch, Walter" sort="Kolch, Walter" uniqKey="Kolch W" first="Walter" last="Kolch">Walter Kolch</name></country><country name="États-Unis"><region name="Virginie"><name sortKey="Conaway, Mark" sort="Conaway, Mark" uniqKey="Conaway M" first="Mark" last="Conaway">Mark Conaway</name></region><name sortKey="Coon, Joshua" sort="Coon, Joshua" uniqKey="Coon J" first="Joshua" last="Coon">Joshua Coon</name><name sortKey="Julian, Bruce A" sort="Julian, Bruce A" uniqKey="Julian B" first="Bruce A." last="Julian">Bruce A. Julian</name><name sortKey="Novak, Jan" sort="Novak, Jan" uniqKey="Novak J" first="Jan" last="Novak">Jan Novak</name><name sortKey="Semmes, O John" sort="Semmes, O John" uniqKey="Semmes O" first="O. John" last="Semmes">O. John Semmes</name><name sortKey="Theodorescu, Dan" sort="Theodorescu, Dan" uniqKey="Theodorescu D" first="Dan" last="Theodorescu">Dan Theodorescu</name><name sortKey="Van Eyk, Jennifer E" sort="Van Eyk, Jennifer E" uniqKey="Van Eyk J" first="Jennifer E." last="Van Eyk">Jennifer E. Van Eyk</name></country><country name="Suisse"><region name="Canton de Genève"><name sortKey="Hochstrasser, Denis" sort="Hochstrasser, Denis" uniqKey="Hochstrasser D" first="Denis" last="Hochstrasser">Denis Hochstrasser</name></region></country><country name="France"><region name="Hauts-de-France"><name sortKey="Massy, Ziad A" sort="Massy, Ziad A" uniqKey="Massy Z" first="Ziad A." last="Massy">Ziad A. Massy</name></region><name sortKey="Schanstra, Joost" sort="Schanstra, Joost" uniqKey="Schanstra J" first="Joost" last="Schanstra">Joost Schanstra</name></country><country name="Australie"><region name="Victoria (État)"><name sortKey="Peter, Karlheinz" sort="Peter, Karlheinz" uniqKey="Peter K" first="Karlheinz" last="Peter">Karlheinz Peter</name></region></country><country name="Danemark"><noRegion><name sortKey="Rossing, Kasper" sort="Rossing, Kasper" uniqKey="Rossing K" first="Kasper" last="Rossing">Kasper Rossing</name></noRegion></country><country name="Thaïlande"><noRegion><name sortKey="Thongboonkerd, Visith" sort="Thongboonkerd, Visith" uniqKey="Thongboonkerd V" first="Visith" last="Thongboonkerd">Visith Thongboonkerd</name></noRegion></country><country name="Japon"><noRegion><name sortKey="Yamamoto, Tadashi" sort="Yamamoto, Tadashi" uniqKey="Yamamoto T" first="Tadashi" last="Yamamoto">Tadashi Yamamoto</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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